Isolation and structure of a new polyether antibiotic, octacyclomycin.

In the course of a screening program for novel antibiotics showing antitumor activity, a cyclic peptide antibiotic sohbumycin was isolated from the culture broth of Streptomyces sp. No. 82-85, which had been isolated from a soil sample collected in Kanagawa prefecture, Japan. The isolation and physico-chemical properties of sohbumycin and fermentation and taxonomy of the producing organism, Streptomyces sp. No. 82-85, was reported in the preceding paper.1} Through careful frac-